Smoothness and Cam Profile

Something that's been bugging me for a bit is that engine Smoothness is not tied AT ALL to Cam profile.
I don't know how many of you have driven something with a big, lumpy cam in it, but they are not exactly "smooth" at low RPM's.
I would think that if you jack up the basic cam profile too far, it should detract from the smoothness of the engine... giving a little more realistic compromise between performance and "luxury" (tameness?). With VVL, the 2nd cam profile wouldn't really affect this, as it only kicks in at high RPM anyway.
I don't know how many of you have driven something with a big, lumpy cam in it, but they are not exactly "smooth" at low RPM's.
I would think that if you jack up the basic cam profile too far, it should detract from the smoothness of the engine... giving a little more realistic compromise between performance and "luxury" (tameness?). With VVL, the 2nd cam profile wouldn't really affect this, as it only kicks in at high RPM anyway.